Research Determinants of NK-cell killing Discover innate checkpoints that regulate the susceptibility and resistance of target cells to NK-cell attack using CRISPR/Cas9 screens NK cell-based cellular therapy Rationally design NK cell-based cellular therapy against liquid and solid cancers for enhanced survival, homing, infiltration, and killing SARS-CoV-2 and NK cells Identify mechanisms of NK-cell recognition of SARS-CoV-2-infected cells and how SARS-CoV-2 evades the immune system
